Tardive dyskinesia is caused by maladaptive synaptic plasticity: A hypothesis

@article{Teo2012TardiveDI,
  title={Tardive dyskinesia is caused by maladaptive synaptic plasticity: A hypothesis},
  author={James T H Teo and Mark J. Edwards and Kailash P. Bhatia},
  journal={Movement Disorders},
  year={2012},
  volume={27}
}
It has been 50 years since the first patients with tardive dyskinesia (TD) were described, but the pathophysiology is only partially understood and effective treatments have remained elusive. Newer atypical antipsychotics with less nonspecific activity at dopamine receptors have not heralded the end of tardive dyskinesia and merely highlight the incomplete understanding of the disorder. 
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TLDR
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