Tapeworm infection reduces epithelial ion transport abnormalities in murine dextran sulfate sodium-induced colitis.

@article{Reardon2001TapewormIR,
  title={Tapeworm infection reduces epithelial ion transport abnormalities in murine dextran sulfate sodium-induced colitis.},
  author={Christopher Reardon and Armand S{\'a}nchez and Cory M Hogaboam and D M McKay},
  journal={Infection and immunity},
  year={2001},
  volume={69 7},
  pages={4417-23}
}
The rat tapeworm Hymenolepis diminuta was used to test the hypothesis that helminth infection could modulate murine colitis. Mice were infected with five H. diminuta cysticercoids, and colitis was evoked via free access to 4% (wt/vol) dextran sulfate sodium (DSS)-containing drinking water for 5 days. BALB/c mice were either infected with H. diminuta and 7 days later exposed to DSS (prophylactic strategy) or started on DSS and infected with H. diminuta 48 h later (treatment strategy). Naive and… CONTINUE READING