Tapentadol abuse and dependence in India.

@article{Mukherjee2020TapentadolAA,
  title={Tapentadol abuse and dependence in India.},
  author={Diptadhi Mukherjee and Lekhansh Shukla and Priya Rani Saha and Jayant Mahadevan and Arun Kandasamy and Prabhat Chand and Vivek Benegal and Pratima Murthy},
  journal={Asian journal of psychiatry},
  year={2020},
  volume={49},
  pages={
          101978
        }
}
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References

SHOWING 1-10 OF 12 REFERENCES
Is tapentadol a potential Trojan horse in the postdextropropoxyphene era in India?
TLDR
These cases highlight the potential of tapentadol in replacing dextropropoxyphene as the widespread prescription opioid of abuse and also emphasize the current controversies regarding opioid control policies in India.
Tapentadol abuse potential: a postmarketing evaluation using a sample of individuals evaluated for substance abuse treatment.
TLDR
Tapentadol abuse was seen infrequently in this study and, on a prescription basis, was less likely to be abused than most of the examined Schedule II analgesics.
Diversion and Illicit Sale of Extended Release Tapentadol in the United States
TLDR
The results indicate that tapentadol ER is rarely sold illicitly in the United States and costs less than other Schedule II opioid products.
Comparative pharmacology and toxicology of tramadol and tapentadol
TLDR
Although more studies are needed to provide clear guidance on the opioid of choice, tapentadol shows some advantages, as it does not require CYP450 system activation and has minimal serotonergic effects, which leads to less side effects and lower abuse liability.
Miotic and subject-rated effects of therapeutic doses of tapentadol, tramadol, and hydromorphone in occasional opioid users
TLDR
The highest tested dose of tapentadol produced a profile of positive effects comparable to that of hydromorphone, whereas tramadolproduced positive and negative subject-rated effects, consistent with previous findings indicating that it has a distinct profile of effects relative to prototypic opioids.
Death Due to Apparent Intravenous Injection of Tapentadol
TLDR
The autopsy findings were consistent with an opiate‐type drug overdose, and indicated no competing cause of death, and the toxicologic features of this case may assist other individuals in evaluating deaths where tapentadol concentration is a factor.
Ilaprazole for the treatment of gastro-esophageal reflux
TLDR
The potential improvements achievable with ilaprazole in the current standard of care for acid-suppressing treatment must be confirmed in large and randomly controlled clinical trials enrolling patients with both erosive and non-erosive reflux disease.
Cost-effectiveness of hepatitis C treatment using generic direct-acting antivirals available in India
TLDR
Treatment with generic DAAs available in India will improve patient outcomes, provide a good value for money within 2 years, and be ultimately cost-saving.
Can Big Data Predict the Rise of Novel Drug Abuse?
TLDR
Despite limitations, Google Trends appears to be a promising compliment to existing data, providing real time data that may allow us to predict drug abuse trends and respond more quickly.
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