Tanshinone IIA-loaded reconstituted high density lipoproteins: Atherosclerotic plaque targeting mechanism in a foam cell model and pharmacokinetics in rabbits.

Abstract

Spherical and discoidal tanshinone IIA-loaded reconstituted high density lipoproteins (TA-rHDL) with different formulations and techniques were prepared and characterized. The targeting mechanism was investigated using a foam cell model. Pharmacokinetics of four TA-rHDL formulations with or without apolipoproteins (apos) after a single dose intravenous… (More)

Topics

Cite this paper

@article{Zhang2012TanshinoneIR, title={Tanshinone IIA-loaded reconstituted high density lipoproteins: Atherosclerotic plaque targeting mechanism in a foam cell model and pharmacokinetics in rabbits.}, author={Wenli Zhang and Jin Li and Jianping Liu and Zimei Wu and Yiming Xu and Ji Wang}, journal={Die Pharmazie}, year={2012}, volume={67 4}, pages={324-30} }