TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy


Targeted T cells are emerging as effective non-toxic therapies for cancer. Multiple elements, however, contribute to the overall pathogenesis of cancer through both distinct and redundant mechanisms. Hence, targeting multiple cancer-specific markers simultaneously could result in better therapeutic efficacy. We created a functional chimeric antigen receptor… (More)
DOI: 10.1038/mtna.2013.32


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@inproceedings{Grada2013TanCARAN, title={TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy}, author={Zakaria Grada and Meenakshi Hegde and Tiara T Byrd and Donald R. Shaffer and Alexia Ghazi and Vita S. Brawley and Amanda Corder and Kurt Sch{\"o}nfeld and Joachim W Koch and Gianpietro Dotti and Helen E Heslop and Stephen Gottschalk and Winfried S. Wels and Matthew L. Baker and Nabil Ahmed}, booktitle={Molecular therapy. Nucleic acids}, year={2013} }