Tamoxifen-loaded lecithin organogel (LO) for topical application: Development, optimization and characterization.

@article{Bhatia2013TamoxifenloadedLO,
  title={Tamoxifen-loaded lecithin organogel (LO) for topical application: Development, optimization and characterization.},
  author={A. Bhatia and B. Singh and K. Raza and S. Wadhwa and O. Katare},
  journal={International journal of pharmaceutics},
  year={2013},
  volume={444 1-2},
  pages={
          47-59
        }
}
Lecithin organogels (LOs) are semi-solid systems with immobilized organic liquid phase in 3-D network of self-assembled gelators. This paper attempts to study the various attributes of LOs, starting from selection of materials, optimization of influential components to LO specific characterization. After screening of various components (type of gelators, organic and aqueous phase) and construction of phase diagrams, a D-optimal mixture design was employed for the systematic optimization of the… Expand
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