Tamoxifen inhibits nerve growth factor-induced proliferation of the human breast cancerous cell line MCF-7.

@article{Chiarenza2001TamoxifenIN,
  title={Tamoxifen inhibits nerve growth factor-induced proliferation of the human breast cancerous cell line MCF-7.},
  author={Andrea Chiarenza and Philip Lazarovici and Laurence Lempereur and Giuseppina Cantarella and Alfredo Bianchi and Renato Bernardini},
  journal={Cancer research},
  year={2001},
  volume={61 7},
  pages={3002-8}
}
An array of polypeptide growth factors contribute to the development of breast cancer, the most common tumor-related cause of death in women of Western countries. Therefore, breast cancer therapy should be aimed at inhibition of growth factor-dependent breast cancerous cell proliferation. However, the relative contribution of each individual factor in the development and maintenance of the transformed phenotype is largely unknown. Here we report for the first time that the proliferative effects… CONTINUE READING

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