Tamoxifen increases the risk of microvascular flap complications in patients undergoing microvascular breast reconstruction.

@article{Kelley2012TamoxifenIT,
  title={Tamoxifen increases the risk of microvascular flap complications in patients undergoing microvascular breast reconstruction.},
  author={Brian P Kelley and Vicente Valero and Min Yi and Steven J. Kronowitz},
  journal={Plastic and reconstructive surgery},
  year={2012},
  volume={129 2},
  pages={305-14}
}
BACKGROUND Tamoxifen citrate (tamoxifen) has been associated with increased rates of thromboembolic events, prompting concerns that it may increase the risk of complications after microvascular breast reconstruction. Some centers have implemented protocols to temporarily stop tamoxifen before microvascular breast reconstruction. The authors sought to determine whether this practice is warranted. METHODS A total of 670 patients underwent delayed microsurgical breast reconstruction at the… CONTINUE READING
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