Tamoxifen and the female genital tract.

  title={Tamoxifen and the female genital tract.},
  author={Austin H N Ugwumadu and Paul L. Carmichael and Patrick Neven},
  journal={International journal of gynecological cancer : official journal of the International Gynecological Cancer Society},
  volume={8 1},
Ugwumadu AHN, Carmichael P, Neven P. Tamoxifen and the female genital tract. Int J Gynecol Cancer 1998; 8: 6-15. Tamoxifen was originally developed by Imperial Chemical Industries (England) (ICI) in 1966 as an anti-estrogenic contraceptive. Ironically, it found a role in the treatment of anovulatory infertility, but its most important application to date is in adjuvant hormonotherapy for breast cancer. Tamoxifen has a complex and poorly understood mix of estrogenic and anti-estrogenic… CONTINUE READING