Tamoxifen and TRAIL synergistically induce apoptosis in breast cancer cells

Abstract

Tamoxifen (TAM), is widely used as a single agent in adjuvant treatment of breast cancer. Here, we investigated the effects of TAM in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in estrogen receptor-α (ER-α)-positive and -negative breast cancer cells. We showed that cotreatment with TAM and TRAIL synergistically induced… (More)
DOI: 10.1038/sj.onc.1210749

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@article{Lagadec2008TamoxifenAT, title={Tamoxifen and TRAIL synergistically induce apoptosis in breast cancer cells}, author={Chann Lagadec and Elias Adriaenssens and R. A. Toillon and Val{\'e}rie Chopin and Rodrigue Romon and Fabien Van Coppenolle and Hubert Hondermarck and Xuefen Le Bourhis}, journal={Oncogene}, year={2008}, volume={27}, pages={1472-1477} }