Tamoxifen advances puberty in the White Leghorn hen.

@article{Jaccoby1992TamoxifenAP,
  title={Tamoxifen advances puberty in the White Leghorn hen.},
  author={S Jaccoby and N. Snapir and Israel Rozenboim and Eyal Arnon and Rina Meidan and Boaz Robinzon},
  journal={British poultry science},
  year={1992},
  volume={33 1},
  pages={101-11}
}
1. Tamoxifen (TAM) administration advances puberty in cockerels. In the present study the effect of TAM administration on the sexual development of White Leghorn hens was studied. 2. Two-week-old White Leghorn females were injected intramuscularly with TAM on alternate days at doses of 0.1 mg (0.1 TM), 1 mg (1TM), 5 mg (5TM) and 10 mg/kg body weight (10TM) respectively, while the controls were injected with maize oil (vehicle). The experiment was terminated at 23 weeks of age, when all the… CONTINUE READING