Tamoxifen: A Protein Kinase C Inhibitor to Treat Mania A Systematic Review and Meta-Analysis of Randomized, Placebo-Controlled Trials

  title={Tamoxifen: A Protein Kinase C Inhibitor to Treat Mania A Systematic Review and Meta-Analysis of Randomized, Placebo-Controlled Trials},
  author={A. Talaei and M. Pourgholami and H. Khatibi-Moghadam and Farhad Faridhosseini and F. Farhoudi and Arash Askari-Noghani and R. Sadeghi},
  journal={Journal of Clinical Psychopharmacology},
  • A. Talaei, M. Pourgholami, +4 authors R. Sadeghi
  • Published 2016
  • Medicine
  • Journal of Clinical Psychopharmacology
  • Objective The aim of this study was to conduct a systematic review of literature to retrieve all randomized controlled trials that evaluated the efficacy of tamoxifen on manic mood episodes and meta-analyze their quantitative results. Methods Four electronic databases were systematically searched from their inception to March 2014: PubMed, Cochrane Library (Cochrane Central Register of Controlled Trials), Scopus, and PsychINFO. Pooled difference in means of changes in mania scores and pooled… CONTINUE READING
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