Tamoxifen, an anticancer drug, is an activator of human aldehyde dehydrogenase 1A1

@article{BelmontDaz2015TamoxifenAA,
  title={Tamoxifen, an anticancer drug, is an activator of human aldehyde dehydrogenase 1A1},
  author={J. Belmont-D{\'i}az and Luis F Calleja-Casta{\~n}eda and Belem Yoval-S{\'a}nchez and J. Rodr{\'i}guez-Zavala},
  journal={Proteins: Structure},
  year={2015},
  volume={83}
}
The modulation of aldehyde dehydrogenase (ALDH) activity has been suggested as a promising option for the prevention or treatment of many diseases. To date, only few activating compounds of ALDHs have been described. In this regard, N‐(1,3‐benzodioxol‐5‐ylmethyl)−2,6‐dichlorobenzamide has been used to protect the heart against ischemia/reperfusion damage. In the search for new modulating ALDH molecules, the binding capability of different compounds to the active site of human aldehyde… Expand
Omeprazole as a potent activator of human cytosolic aldehyde dehydrogenase ALDH1A1.
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