Tamm-Horsfall protein in recurrent calcium kidney stone formers with positive family history: abnormalities in urinary excretion, molecular structure and function

@article{Jaggi2007TammHorsfallPI,
  title={Tamm-Horsfall protein in recurrent calcium kidney stone formers with positive family history: abnormalities in urinary excretion, molecular structure and function},
  author={Markus Jaggi and Yasushi Nakagawa and Ljerka Zipperle and Bernhard Hess},
  journal={Urological Research},
  year={2007},
  volume={35},
  pages={55-62}
}
Tamm-Horsfall protein (THP) powerfully inhibits calcium oxalate crystal aggregation, but structurally abnormal THPs from recurrent calcium stone formers may promote crystal aggregation. Therefore, increased urinary excretion of abnormal THP might be of relevance in nephrolithiasis. We studied 44 recurrent idiopathic calcium stone formers with a positive… CONTINUE READING