Taming the Past: Ancient DNA and the Study of Animal Domestication.

@article{MacHugh2017TamingTP,
  title={Taming the Past: Ancient DNA and the Study of Animal Domestication.},
  author={David Evan MacHugh and Greger Larson and Ludovic Orlando},
  journal={Annual review of animal biosciences},
  year={2017},
  volume={5},
  pages={
          329-351
        }
}
During the last decade, ancient DNA research has been revolutionized by the availability of increasingly powerful DNA sequencing and ancillary genomics technologies, giving rise to the new field of paleogenomics. In this review, we show how our understanding of the genetic basis of animal domestication and the origins and dispersal of livestock and companion animals during the Upper Paleolithic and Neolithic periods is being rapidly transformed through new scientific knowledge generated with… 
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References

SHOWING 1-10 OF 159 REFERENCES

A population genetics view of animal domestication.

Documenting Domestication: New Genetic and Archaeological Paradigms

This groundbreaking volume for the first time brings together leading archaeologists and biologists working on the domestication of both plants and animals to consider a wide variety of archaeological and genetic approaches to tracing the origin and dispersal of domesticates.

Widespread origins of domestic horse lineages.

Domestication entails control of wild species and is generally regarded as a complex process confined to a restricted area and culture. Previous DNA sequence analyses of several domestic species have…

The Evolution of Animal Domestication

A framework for understanding how unconscious selection characterized the earliest steps of animal domestication and the role of introgression and the importance of relaxed and positive selection in shaping modern domestic phenotypes and genomes is presented.

Using Ancient DNA to Understand Evolutionary and Ecological Processes

This work has shown that genome-level surveys of ancient populations will play an increasingly important role in shaping modern populations and the future of paleoecological systems.

Ancient and modern DNA reveal dynamics of domestication and cross-continental dispersal of the dromedary

Compared with other livestock, which show a long history of gene flow with their wild ancestors, the dromedary finds a high initial diversity relative to the native distribution of the wild ancestor on the Arabian Peninsula and to the brief coexistence of early-domesticated and wild individuals.

Genetics and animal domestication: new windows on an elusive process

Issues related to the terminology associated with domestication, the possibility of domestication genes, and the promise and problems of genetics to answer the fundamental questions associated withDomestication are discussed.

A Paleogenomic Perspective on Evolution and Gene Function: New Insights from Ancient DNA

The origins and growth of this field are reviewed and how challenges owing to the limited amount of DNA available for analysis and the possibility of contamination by modern material have been overcome are explained.

The future of ancient DNA: Technical advances and conceptual shifts

In this review, important areas of future technical and conceptual progress are highlighted and research topics in the rapidly growing field of palaeogenomics are discussed.

Mitochondrial genomes from modern horses reveal the major haplogroups that underwent domestication

Now that the major horse haplogroups have been defined, each with diagnostic mutational motifs (in both the coding and control regions), these haplotypes could be easily used to classify well-preserved ancient remains, assess the haplogroup variation of modern breeds, and evaluate the possible role of mtDNA backgrounds in racehorse performance.
...