Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins.

@article{Kitano2002TamalinAP,
  title={Tamalin, a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins.},
  author={Jun Kitano and Kouji Kimura and Yoshimitsu Yamazaki and Takeshi Soda and Ryuichi Shigemoto and Y. Karasawa N. Nakajima and Shigetada Nakanishi},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2002},
  volume={22 4},
  pages={1280-9}
}
In this investigation, we report identification and characterization of a 95 kDa postsynaptic density protein (PSD-95)/discs-large/ZO-1 (PDZ) domain-containing protein termed tamalin, also recently named GRP1-associated scaffold protein (GRASP), that interacts with group 1 metabotropic glutamate receptors (mGluRs). The yeast two-hybrid system and in vitro pull-down assays indicated that the PDZ domain-containing, amino-terminal half of tamalin directly binds to the class I PDZ-binding motif of… CONTINUE READING
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Interaction of the C-terminal tail region of the metabotropic glutamate receptor 7 with the protein kinase C substrate PICK1

  • O El Far, J Airas, E Wischmeyer, RB Nehring, A Karschin, H Betz
  • Eur J Neurosci
  • 2000
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