Tales of tails: regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation, and aging.

@article{Weng1997TalesOT,
  title={Tales of tails: regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation, and aging.},
  author={Nan-ping Weng and Larry D. Palmer and Bruce L Levine and H Clifford Lane and Carl H June and Richard J Hodes},
  journal={Immunological reviews},
  year={1997},
  volume={160},
  pages={43-54}
}
Telomerase activity and the regulation of telomere length are factors which have been implicated in the control of cellular replication. These variables have been examined during human lymphocyte development, differentiation, activation, and aging. It was found that telomere length of peripheral blood CD4+ T cells decreases with age as well as with differentiation from naive to memory cells in vivo, and decreases with cell division in vitro. These results provide evidence that telomere length… CONTINUE READING

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