Tales of Human Migration, Admixture, and Selection in Africa.

@article{Schlebusch2018TalesOH,
  title={Tales of Human Migration, Admixture, and Selection in Africa.},
  author={Carina M. Schlebusch and Mattias Jakobsson},
  journal={Annual review of genomics and human genetics},
  year={2018},
  volume={19},
  pages={
          405-428
        }
}
In the last three decades, genetic studies have played an increasingly important role in exploring human history. They have helped to conclusively establish that anatomically modern humans first appeared in Africa roughly 250,000-350,000 years before present and subsequently migrated to other parts of the world. The history of humans in Africa is complex and includes demographic events that influenced patterns of genetic variation across the continent. Through genetic studies, it has become… 

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References

SHOWING 1-10 OF 147 REFERENCES
Chad Genetic Diversity Reveals an African History Marked by Multiple Holocene Eurasian Migrations
Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America
TLDR
The analysis of the genetic diversity of Bantu speakers revealed adaptive introgression of genes that likely originated in other African populations, including specific immune-related genes, and applied this information to African Americans suggests that gene flow from Africa into the Americas was more complex than previously thought.
A genomic view of the peopling of the Americas.
TLDR
Whole genome studies enhanced by technological breakthroughs in ancient DNA now provide evidence of a sequence of events involving initial migration from a structured Northeast Asian source population, followed by a divergence into northern and southern Native American lineages.
Genomic Variation in Seven Khoe-San Groups Reveals Adaptation and Complex African History
TLDR
Genetic variation in various sub-Saharan populations did not localize the origin of modern humans to a single geographic region within Africa; instead, it indicated a history of admixture and stratification, and illustrated the importance of African genomic diversity in understanding human evolutionary history.
The genetic prehistory of southern Africa
TLDR
It is found that all individuals derive at least a few percent of their genomes from admixture with non-Khoisan populations that began ∼1,200 years ago, supporting the hypothesis of an ancient link between southern and eastern Africa.
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans
TLDR
It is found that African hunter-gatherer populations today remain highly differentiated, encompassing major components of variation that are not found in other African populations, and tend to have the lowest levels of genome-wide linkage disequilibrium among 27 African populations.
The Genetic Structure and History of Africans and African Americans
TLDR
A detailed genetic analysis of most major groups of African populations is provided, suggesting that Africans represent 14 ancestral populations that correlate with self-described ethnicity and shared cultural and/or linguistic properties.
The dawn of human matrilineal diversity.
Origins and Genetic Legacy of Neolithic Farmers and Hunter-Gatherers in Europe
TLDR
The results suggest that migration from southern Europe catalyzed the spread of agriculture and that admixture in the wake of this expansion eventually shaped the genomic landscape of modern-day Europe.
...
...