Takotsubo cardiomyopathy and transient global amnesia: a shared aetiology.


Takotsubo cardiomyopathy (TTC) is associated with acute, reversible left ventricular (LV) dysfunction, while transient global amnesia (TGA) is a reversible disorder of the brain characterised by anterograde amnesia. We report an unusual case of TTC occurring concurrently in a patient with TGA, and propose that catecholamine surge induced cerebral venous congestion and cardiotoxicity is the shared aetiology that leads to the concurrent manifestation of these conditions. TTC and TGA are reversible disorders that can occur concurrently in a subset of patients due to a unifying aetiology, catecholamine excess, leading to pathophysiological changes within the brain and the myocardium.

DOI: 10.1136/bcr-2017-219472

Cite this paper

@article{Sajeev2017TakotsuboCA, title={Takotsubo cardiomyopathy and transient global amnesia: a shared aetiology.}, author={Jithin Sajeev and Anoop Koshy and Kevin Rajakariar and Gary Gordon}, journal={BMJ case reports}, year={2017}, volume={2017} }