Takotsubo Cardiomyopathy and 5-Fluorouracil: Getting to the Heart of the Matter

  title={Takotsubo Cardiomyopathy and 5-Fluorouracil: Getting to the Heart of the Matter},
  author={Stephanie Hui-Su Lim and Sharon Mary Wilson and Arnagretta Hunter and Jane H Hill and Philip J. Beale},
  booktitle={Case reports in oncological medicine},
Takotsubo cardiomyopathy is a rare but increasingly recognized phenomenon, which can occur as a side-effect of chemotherapeutic agents, in particular, the antimetabolite 5-fluorouracil. We describe a case of delayed Takotsubo cardiomyopathy after 3 weeks of adjuvant 5-fluorouracil for resected rectal adenocarcinoma in a 66-year-old female, supported by angiographic, electrocardiographic, and echocardiographic features. As a complication, she developed an apical mural thrombus with subsequent… CONTINUE READING


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