Taking Advantage of the Systemic Immune System to Cure Brain Diseases

@article{Yong2009TakingAO,
  title={Taking Advantage of the Systemic Immune System to Cure Brain Diseases},
  author={Voon Wee Yong and Serge Rivest},
  journal={Neuron},
  year={2009},
  volume={64},
  pages={55-60}
}
The systemic immune system has the ability to modulate multiple brain functions, including autonomic responses, glial reactivity following neural injuries, and neuronal excitability. Immune stimuli also influence microglia subpopulations originating from blood progenitors, and neuroprotective and reparative capacities of blood-derived microglia were recently described in mouse models of spinal cord injury and brain disorders. Furthermore, reparative roles for various immune subsets have been… CONTINUE READING

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