Takayasu's arteritis and Crohn's disease: an unusual association. Report on two cases.


Two cases of Takayasu's arteritis associated with Crohn's disease of the colon are described, both of which occurring in young female patients. In the first case, the vasculitic process was widespread, involving the aortic arch, the abdominal aorta, the renal arteries and the left iliac artery, similar to the angiographic "Indian" pattern. The second case presented a typical "Japanese" aortic arch involvement. In the first patient, Crohn's disease appeared to have been present prior to Takayasu's arteritis, vice versa in the second case; steroid treatment, assigned for both diseases might, however, have modified their natural evolution. The association is rare. Moreover, the coexistence of two immune-mediated diseases in the same subject is unusual as they are generally considered to be independent. Hypotheses concerning their possible inter-relationship are advanced.

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@article{Biagi2001TakayasusAA, title={Takayasu's arteritis and Crohn's disease: an unusual association. Report on two cases.}, author={Pierluigi Biagi and Raimundo M Castro and Giuseppe Campanella and Giuseppe Parisi and A R Gobbini and G Vedovini}, journal={Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver}, year={2001}, volume={33 6}, pages={487-91} }