Tailoring fiber diameter in electrospun poly(epsilon-caprolactone) scaffolds for optimal cellular infiltration in cardiovascular tissue engineering.

@article{Balguid2009TailoringFD,
  title={Tailoring fiber diameter in electrospun poly(epsilon-caprolactone) scaffolds for optimal cellular infiltration in cardiovascular tissue engineering.},
  author={A Angelique Balguid and Adriano A. Mol and Mieke H van Marion and Ruud A. Bank and Carlijn V C Bouten and Frank T. P. Baaijens},
  journal={Tissue engineering. Part A},
  year={2009},
  volume={15 2},
  pages={
          437-44
        }
}
Despite the attractive features of nanofibrous scaffolds for cell attachment in tissue-engineering (TE) applications, impeded cell ingrowth has been reported in electrospun scaffolds. Previous findings have shown that the scaffold can function as a sieve, keeping cells on the scaffold surface, and that cell migration into the scaffold does not occur in time. Because fiber diameter is directly related to the pore size of an electrospun scaffold, the objective of this study was to systematically… CONTINUE READING
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