Tailored second-line therapy in asthmatic children with the Arg(16) genotype.

Abstract

The Arg(16) β(2) receptor genotype confers increased susceptibility to exacerbations in asthmatic children taking regular LABA (long-acting β(2) agonists). We therefore evaluated using montelukast as an alternative to salmeterol as tailored second-line asthma controller therapy in children expressing this susceptible genotype. A total of 62 persistent… (More)
DOI: 10.1042/CS20120528

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