Tail tendon break time: a biomarker of aging?

@article{Sloane2011TailTB,
  title={Tail tendon break time: a biomarker of aging?},
  author={Lauren B. Sloane and Joseph T. Stout and S N Austad and Gerald E Mcclearn},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  year={2011},
  volume={66 3},
  pages={287-94}
}
Research has attempted to identify biomarkers of aging that are predictive of longevity and specific age-related changes during animal life span. Tail tendon break time (TTBT), one presumed biomarker, measures collagen cross-linking, known to increase with age. Significant differences in the rate of increase of TTBT with age have been reported between mouse strains and animal species. We measured both TTBT and longevity in C57BL/6J, DBA/2J, and 23 recombinant inbred (RI) strains (B×D RIs), with… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-3 of 3 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Healthspan, translation, and new outcomes for animal studies of aging.

The journals of gerontology. Series A, Biological sciences and medical sciences • 2009

PohnB6F1: a cross of wild and domestic mice that is a new model of extended female reproductive life span.

The journals of gerontology. Series A, Biological sciences and medical sciences • 2007

Similar Papers

Loading similar papers…