Taenia crassiceps infection and its excreted/secreted products inhibit STAT1 activation in response to IFN-γ.

@article{BecerraDaz2014TaeniaCI,
  title={Taenia crassiceps infection and its excreted/secreted products inhibit STAT1 activation in response to IFN-γ.},
  author={Mireya Becerra-D{\'i}az and Luis I Terrazas},
  journal={International journal for parasitology},
  year={2014},
  volume={44 9},
  pages={613-23}
}
It is well understood that helminth infections modulate the immune responses of their hosts but the mechanisms involved in this modulation are not fully known. Macrophages and dendritic cells appear to be consistently affected during this type of infection and are common target cells for helminth-derived molecules. In this report, we show that macrophages obtained from chronically Taenia crassiceps-infected mice displayed an impaired response to recombinant murine IFN-γ, but not to recombinant… CONTINUE READING
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Taenia crassice response to IFNc

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Terrazas / International Journal for Parasitology

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