Tadalafil for the treatment of pulmonary arterial hypertension.

@article{Frey2012TadalafilFT,
  title={Tadalafil for the treatment of pulmonary arterial hypertension.},
  author={Maria Klara Frey and Irene M Lang},
  journal={Expert opinion on pharmacotherapy},
  year={2012},
  volume={13 5},
  pages={747-55}
}
INTRODUCTION Pulmonary arterial hypertension (PAH) is a progressive occlusive disease affecting the pulmonary vasculature; it carries a poor prognosis. Because right ventricular failure is the key feature of deterioration in PAH patients, vasodilator treatments relieving right ventricular afterload have gained ground in the treatment of this disorder. Phosphodiesterase-5 inhibitors are effective and well tolerated vasodilators that were originally developed for erectile dysfunction. Tadalafil… CONTINUE READING
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