Tacrolimus-induced lung injury in a rheumatoid arthritis patient with interstitial pneumonitis

  title={Tacrolimus-induced lung injury in a rheumatoid arthritis patient with interstitial pneumonitis},
  author={Y. Miwa and T. Isozaki and K. Wakabayashi and T. Odai and M. Matsunawa and N. Yajima and M. Negishi and H. Ide and T. Kasama and M. Adachi and Tomoyuki Hisayuki and T. Takemura},
  journal={Modern Rheumatology},
  • Y. Miwa, T. Isozaki, +9 authors T. Takemura
  • Published 2008
  • Medicine
  • Modern Rheumatology
  • A 74-year-old woman was experiencing rheumatoid arthritis complicated with interstitial pneumonitis (IP), and tacrolimus treatment was started. She presented with dyspnea. Chest X-ray and computed tomography (CT) showed ground-glass opacity and IP. Although tacrolimus was stopped, she died of respiratory failure. At autopsy, both the upper and lower lung fields showed usual IP and the organizing stage of diffuse alveolar damage. The former is common, but the latter is uncommon, suggesting… CONTINUE READING
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