Tacrolimus as an alternative to cyclosporine in the maintenance phase of immunosuppressive therapy for severe aplastic anemia in children.

@article{Alsultan2009TacrolimusAA,
  title={Tacrolimus as an alternative to cyclosporine in the maintenance phase of immunosuppressive therapy for severe aplastic anemia in children.},
  author={Abdulrahman Alsultan and Neil A. Goldenberg and Nicole A Kaiser and Douglas Kim Graham and Tanna Hays},
  journal={Pediatric blood & cancer},
  year={2009},
  volume={52 5},
  pages={
          626-30
        }
}
OBJECTIVE Given the paucity of data on the use of agents other than cyclosporine (CsA) in the maintenance phase of immunosuppressive therapy (IST) for severe aplastic anemia (SAA) in children, we sought to describe our experience with tacrolimus in pediatric SAA, and to compare outcomes with a preceding series of patients who received CsA. METHODS Eight patients with SAA diagnosed between 2003 and 2008 for whom no human leukocyte antigen (HLA)-matched sibling donor was identified underwent… CONTINUE READING
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