Tackling the legs of mannan-binding lectin.

  title={Tackling the legs of mannan-binding lectin.},
  author={Erhard Hohenester},
  volume={19 11},
The recognition of pathogen surfaces by mannan-binding lectin activates MASP proteases, leading to complement activation. A crystal structure by Gingras et al. (2011) in this issue of Structure now shows how the collagen-like stems of mannan-binding lectin bind MASP-1 through a minimalist set of interactions. 

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