Tackling the Challenges of Clinical Trials in Palliative Care

@article{Currow2012TacklingTC,
  title={Tackling the Challenges of Clinical Trials in Palliative Care},
  author={David Christopher Currow and Meera R. Agar and Amy P. Abernethy},
  journal={Pharmaceutical Medicine},
  year={2012},
  volume={25},
  pages={7-15}
}
There is an ethical imperative to provide the best quality of care for all people, including people at the end of life. In order to provide such care, each intervention used in clinical practice must be tested objectively for net clinical benefit (response and toxicity). For pharmacological and non-pharmacological interventions, the gold standard of evidence remains a phase III randomized, controlled study. In palliative care, there is a gradually emerging evidence base for clinical practice… Expand
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