Tachykinins in the emerging immune system: relevance to bone marrow homeostasis and maintenance of hematopoietic stem cells.

@article{Greco2004TachykininsIT,
  title={Tachykinins in the emerging immune system: relevance to bone marrow homeostasis and maintenance of hematopoietic stem cells.},
  author={Steven Greco and Kelly E. Corcoran and Kyung Jin Cho and Pranela Rameshwar},
  journal={Frontiers in bioscience : a journal and virtual library},
  year={2004},
  volume={9},
  pages={1782-93}
}
The mammalian tachykinins mediate crosstalk within the neural-immune-hematopoietic axis. Hematopoiesis occurs in the adult bone marrow (BM) and it is described as the method by which the immune system is replenished by a finite number of hematopoietic stem cells (HSC). These cells are found in the BM close to the endosteum where the oxygen level is the lowest. The BM is also resident to mesenchymal stem cell (MSC). The functions of HSC depend on the MSC to generate the supporting stromal cells… CONTINUE READING

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Mesenchymal stem cells

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