Tachykinins and their receptors: contributions to physiological control and the mechanisms of disease.

Abstract

The tachykinins, exemplified by substance P, are one of the most intensively studied neuropeptide families. They comprise a series of structurally related peptides that derive from alternate processing of three Tac genes and are expressed throughout the nervous and immune systems. Tachykinins interact with three neurokinin G protein-coupled receptors. The… (More)
DOI: 10.1152/physrev.00031.2013

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