Tachykinin receptor expression and function in human esophageal smooth muscle.

@article{Kovac2006TachykininRE,
  title={Tachykinin receptor expression and function in human esophageal smooth muscle.},
  author={Jason Ronald Kovac and Tom Chrones and Harold G. Preiksaitis and Stephen Michael Sims},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={2006},
  volume={318 2},
  pages={513-20}
}
Tachykinins are present in enteric nerves of the gastrointestinal tract and cause contraction of esophageal smooth muscle; however, the mechanisms involved are not understood. Our aim was to characterize tachykinin signaling in human esophageal smooth muscle. We investigated functional effects of tachykinins on human esophageal smooth muscle using tension recordings and isolated cells, receptor expression with reverse transcription (RT)-polymerase chain reaction (PCR) and immunoblotting… CONTINUE READING

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