Tachykinin NK3 and NK1 receptor activation elicits secretion from porcine airway submucosal glands.

@article{Phillips2003TachykininNA,
  title={Tachykinin NK3 and NK1 receptor activation elicits secretion from porcine airway submucosal glands.},
  author={Jonathan E Phillips and John A. Hey and Michel R. Corboz},
  journal={British journal of pharmacology},
  year={2003},
  volume={138 1},
  pages={
          254-60
        }
}
1 We presently characterized the tachykinin receptor subtypes, using tachykinin receptor agonists and selective antagonists, that induce submucosal gland fluid flux (J(G)) from porcine tracheal explants with the hillocks technique. We also investigated the effects of the tachykinin receptor agonists on the electrophysiologic parameters of the tracheal epithelium in Ussing chambers. 2 The NK(1) tachykinin receptor agonist substance P (SP, 1 microM) and the NK(3) tachykinin receptor agonist… CONTINUE READING

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