Tableting of coated ketoprofen pellets.

  title={Tableting of coated ketoprofen pellets.},
  author={I M el-Mahdi and Patrick B Deasy},
  journal={Journal of microencapsulation},
  volume={17 2},
Ketoprofen pellets were prepared by the method of extrusion-spheronization, and a film coating of guar gum and Eudragit NE was applied to drug cores using pan technology. In an attempt to design a tablet which, on peroral administration, disintegrates rapidly, releasing intact coated pellets which maintain the integrity of both the cores and their release retarding membrane, Avicel PH101, lactose DT and magnesium stearate were used as excipients to prepare tablets comprising ketoprofen pellets… CONTINUE READING