Tablet preformulations of indomethacin-loaded mesoporous silicon microparticles.

Abstract

In this study, indomethacin-loaded thermally oxidized mesoporous silicon microparticles (TOPSi-IMC) were formulated into tablets with excipients in order to improve the dissolution and permeability properties of the poorly soluble drug. Formulations of TOPSi-IMC particles and excipients were prepared at different TOPSi-IMC particle ratios (25, 30 and 35… (More)
DOI: 10.1016/j.ijpharm.2011.10.040

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