Tabby pattern genetics – a whole new breed of cat

@article{Kaelin2010TabbyPG,
  title={Tabby pattern genetics – a whole new breed of cat},
  author={Christopher B. Kaelin and Gregory S. Barsh},
  journal={Pigment Cell \& Melanoma Research},
  year={2010},
  volume={23}
}
Much of what we know about pigment cell biology comes from studying laboratory mice, yet the conservation of gene action and interaction across domesticated animals, including horses, cattle, pigs, and dogs, is firm evidence that most aspects of color variation are conserved in mammals. [] Key Method The nomenclature has become complicated; similar to Eizirik et al. (2010), we use lower case roman to describe the

Mining the 99 Lives Cat Genome Sequencing Consortium database implicates genes and variants for the Ticked locus in domestic cats ( Felis catus )

Bioinformatic and molecular modeling analysis suggests that changes disrupt a key disulfide bond in the Dkk4 cysteine-rich domain 1 or DKK4 signal peptide cleavage respectively.

Mining the 99 Lives Cat Genome Sequencing Consortium database implicates genes and variants for the Ticked locus in domestic cats (Felis catus)

Bioinformatic and molecular modeling analysis suggests that changes in the Ticked locus disrupt a key disulfide bond in the Dkk4 cysteine‐rich domain 1 or DKK4 signal peptide cleavage respectively.

Genetics of pigmentation in dogs and cats.

A molecular genetic review of pigmentary variation in dogs and cats is presented using a nomenclature and logical framework established by early leaders in the field to provide insight into areas that transcend pigment cell biology.

Developmental genetics of color pattern establishment in cats

The results bring molecular understanding to how the leopard got its spots, suggest that similar mechanisms underlie periodic color pattern and periodic hair follicle spacing, and identity new targets for diverse pattern variation in other mammals.

How the Leopard Hides Its Spots: ASIP Mutations and Melanism in Wild Cats

The occurrence of melanism (darkening of the background coloration) is documented in 13 felid species, in some cases reaching high frequencies at the population level. Recent analyses have indicated

Genetic Architecture of Skewed X Inactivation in the Laboratory Mouse

It is concluded that Xcea is either a derived allele that arose concurrently with the domestication of fancy mice but prior the derivation of most classical inbred strains or a rare allele in the wild, and that each mouse taxa examined has a different functional Xce allele.

Who’s behind that mask and cape? The Asian leopard cat’s Agouti (ASIP) allele likely affects coat colour phenotype in the Bengal cat breed

The compound heterozygote state suggests the leopard cat allele, in combination with the recessive non-agouti allele, influences Bengal markings, producing a darker, yet not completely melanistic coat.

Marcadores Genéticos del Color para Determinar la Estructura Genética de Gatos Domésticos (Felis catus) en Zonas Rurales de Lorica, Colombia

La estructura genetica de gatos domesticos (Felis catus) en ambientes rurales de Lorica, Colombia fue analizada, utilizando marcadores morfologicos del color y se encontro diferencias entre poblaciones y poco flujo genetico entre ellas.

References

SHOWING 1-8 OF 8 REFERENCES

Defining and Mapping Mammalian Coat Pattern Genes: Multiple Genomic Regions Implicated in Domestic Cat Stripes and Spots

It is hypothesized that mammalian patterned coats are formed by two distinct processes: a spatially oriented developmental mechanism that lays down a species-specific pattern of skin cell differentiation and a pigmentation-oriented mechanism that uses information from the preestablished pattern to regulate the synthesis of melanin profiles.

A study of variation in Singapore cats

The purpose of this paper is to find out to what extent there are regional differences in gene fiequencies and in quantitative characters in cat populations in different parts of the world, and what light these facts throw on the evolution of the domestic cat and on evolutionary phenomena in general.

Mutation in the melanocortin 1 receptor is associated with amber colour in the Norwegian Forest Cat.

It is concluded that amber colour in NFCs is caused by a single MC1R allele called e, which has never been documented.

A model for generating aspects of zebra and other mammalian coat patterns.

  • J. Bard
  • Biology
    Journal of theoretical biology
  • 1981

Gene frequencies in London's cats

The hypothesis of random mating was tested by using the results for yellow and tortoiseshell, and was found satisfactory, andGene frequencies were estimated on this hypothesis, and a significant tendency for male castration to increase hair length.

Inheritance of coat‐color in cats

Comparative genetics of coat colour in mammals.

O'Brien's

  • 1959