Tabby pattern genetics – a whole new breed of cat

@article{Kaelin2010TabbyPG,
  title={Tabby pattern genetics – a whole new breed of cat},
  author={Christopher B. Kaelin and Gregory S. Barsh},
  journal={Pigment Cell \& Melanoma Research},
  year={2010},
  volume={23}
}
  • C. Kaelin, G. Barsh
  • Published 1 August 2010
  • Biology, Medicine
  • Pigment Cell & Melanoma Research
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References

SHOWING 1-8 OF 8 REFERENCES
Defining and Mapping Mammalian Coat Pattern Genes: Multiple Genomic Regions Implicated in Domestic Cat Stripes and Spots
TLDR
It is hypothesized that mammalian patterned coats are formed by two distinct processes: a spatially oriented developmental mechanism that lays down a species-specific pattern of skin cell differentiation and a pigmentation-oriented mechanism that uses information from the preestablished pattern to regulate the synthesis of melanin profiles. Expand
A study of variation in Singapore cats
TLDR
The purpose of this paper is to find out to what extent there are regional differences in gene fiequencies and in quantitative characters in cat populations in different parts of the world, and what light these facts throw on the evolution of the domestic cat and on evolutionary phenomena in general. Expand
Mutation in the melanocortin 1 receptor is associated with amber colour in the Norwegian Forest Cat.
TLDR
It is concluded that amber colour in NFCs is caused by a single MC1R allele called e, which has never been documented. Expand
A model for generating aspects of zebra and other mammalian coat patterns.
  • J. Bard
  • Biology, Medicine
  • Journal of theoretical biology
  • 1981
TLDR
Analysis of a spotted zebra in the light of the model provides evidence that zebra stripes arise from the inhibition rather than the stimulation of melanin; their pattern is thus of white stripes on a black background. Expand
Gene frequencies in London's cats
  • A. Searle
  • Biology, Medicine
  • Journal of Genetics
  • 2008
TLDR
The hypothesis of random mating was tested by using the results for yellow and tortoiseshell, and was found satisfactory, andGene frequencies were estimated on this hypothesis, and a significant tendency for male castration to increase hair length. Expand
Comparative genetics of coat colour in mammals.
O'Brien's
  • 1959
Inheritance of coat‐color in cats