Corpus ID: 6680748

TYROSINE HYDROXYLASE. THE INITIAL STEP IN NOREPINEPHRINE BIOSYNTHESIS.

@article{Nagatsu1964TYROSINEHT,
  title={TYROSINE HYDROXYLASE. THE INITIAL STEP IN NOREPINEPHRINE BIOSYNTHESIS.},
  author={T. Nagatsu and M. Levitt and S. Udenfriend},
  journal={The Journal of biological chemistry},
  year={1964},
  volume={239},
  pages={
          2910-7
        }
}
  • T. Nagatsu, M. Levitt, S. Udenfriend
  • Published 1964
  • Biology, Medicine
  • The Journal of biological chemistry
  • After demonstration of the decarboxylation of 3,4-dihydroxyphenylalanine (dopa)’ to dopamine (I), the pathway for biosynthesis of norepinephrine shown in Fig. 1 was proposed. Although evidence for this pathway was well established by isot,opic procedures (2, 3), it was not until 1960 that Levin, Levenberg, and Kaufman (4) succeeded in isolating and characterizing the third enzyme in the series, dopamine-B-oxidase (@hydroxylase). The enzyme responsible for converting tyrosine to dopa has… CONTINUE READING
    Tyrosine, phenylalanine, and catecholamine synthesis and function in the brain.
    • 307
    • PDF

    References

    Publications referenced by this paper.
    hp://w w w .jb.org/ D ow nladed from Toshiharu Nagatsu, Morton Levitt and Sidney Udenfriend BIOSYNTHESIS Tyrosine Hydroxylase: THE INITIAL STEP IN NOREPINEPHRINE
    • 1955