TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer

@inproceedings{Xu2014TXNL1XRCC1PR,
  title={TXNL1-XRCC1 pathway regulates cisplatin-induced cell death and contributes to resistance in human gastric cancer},
  author={Wenxiang Xu and Shuhong Wang and Qian-ying Chen and Yongzhan Zhang and Pin Ni and Xiaogang Wu and Jiumeng Zhang and Fulin Qiang and Ai-ling Li and O. D. R{\o}e and Shu-hang Xu and Mei Legam Wang and R Zhang and Jin-Yi Zhou},
  booktitle={Cell Death and Disease},
  year={2014}
}
Cisplatin is a cytotoxic platinum compound that triggers DNA crosslinking induced cell death, and is one of the reference drugs used in the treatment of several types of human cancers including gastric cancer. However, intrinsic or acquired drug resistance to cisplatin is very common, and leading to treatment failure. We have recently shown that reduced expression of base excision repair protein XRCC1 (X-ray repair cross complementing group1) in gastric cancerous tissues correlates with a… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 22 CITATIONS

Enolase 1 stimulates glycolysis to promote chemoresistance in gastric cancer

  • Oncotarget
  • 2017
VIEW 5 EXCERPTS
CITES METHODS, RESULTS & BACKGROUND
HIGHLY INFLUENCED

JWA reverses cisplatin resistance via the CK2—XRCC1 pathway in human gastric cancer cells

  • Cell Death and Disease
  • 2014
VIEW 5 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

KDM 5 B demethylates H 3 K 4 to recruit XRCC 1 and promote chemoresistance

VIEW 4 EXCERPTS
CITES BACKGROUND & METHODS
HIGHLY INFLUENCED

Newcastle disease virus V protein inhibits apoptosis in DF-1 cells by downregulating TXNL1

  • Veterinary research
  • 2018
VIEW 3 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

MiR-99a and MiR-491 Regulate Cisplatin Resistance in Human Gastric Cancer Cells by Targeting CAPNS1

  • International journal of biological sciences
  • 2016
VIEW 3 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

The roles of glucose metabolic reprogramming in chemo- and radio-resistance

  • Journal of experimental & clinical cancer research : CR
  • 2019
VIEW 1 EXCERPT
CITES BACKGROUND

CCL2-SQSTM1 positive feedback loop suppresses autophagy to promote chemoresistance in gastric cancer

  • International journal of biological sciences
  • 2018
VIEW 2 EXCERPTS
CITES BACKGROUND

Similar Papers

Loading similar papers…