TWEAK/Fn14 Signaling Involvement in the Pathogenesis of Cutaneous Disease in the MRL/lpr Model of Spontaneous Lupus

Abstract

Tumor necrosis factor (TNF)-like weak inducer of apoptosis (TWEAK, TNFSF12) and its sole receptor Fn14, belonging to the TNF ligand and receptor superfamilies respectively, are involved in cell survival and cytokine production. The role of TWEAK/Fn14 interactions in the pathogenesis of cutaneous lupus has not been explored. TWEAK treatment of murine PAM212… (More)
DOI: 10.1038/jid.2015.124

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@inproceedings{Doerner2015TWEAKFn14SI, title={TWEAK/Fn14 Signaling Involvement in the Pathogenesis of Cutaneous Disease in the MRL/lpr Model of Spontaneous Lupus}, author={Jessica Doerner and Jing Wen and Yumin Xia and Karin Blecher Paz and David O. Schairer and Lan Wu and Samantha A. Chalmers and Peter M. Izmirly and Jennifer S. Michaelson and Linda Burkly and Adam Friedman and Chaim Putterman}, booktitle={The Journal of investigative dermatology}, year={2015} }