TT virus (TTV) loads associated with different peripheral blood cell types and evidence for TTV replication in activated mononuclear cells.

@article{Maggi2001TTV,
  title={TT virus (TTV) loads associated with different peripheral blood cell types and evidence for TTV replication in activated mononuclear cells.},
  author={F. Maggi and Claudia Fornai and Lucia Zaccaro and A Morrica and Marialinda Vatteroni and Patrizia Isola and Santino Marchi and Angelo Ricchiuti and Mauro Pistello and Mauro Bendinelli},
  journal={Journal of medical virology},
  year={2001},
  volume={64 2},
  pages={190-4}
}
TT virus (TTV) loads associated with the peripheral blood cells of seven patients known to carry the virus in plasma were investigated by real-time PCR. Whereas red cells/platelets were uniformly negative, six and four patients yielded positive peripheral blood mononuclear cells (PBMCs) and polymorphonuclear leukocytes, respectively, but viral titres were generally low. Fractionation of PBMCs into monocyte- and B, T4, and T8 lymphocyte-enriched subpopulations showed no pattern in the viral… CONTINUE READING

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