TSSer: an automated method to identify transcription start sites in prokaryotic genomes from differential RNA sequencing data

@article{Jorjani2014TSSerAA,
  title={TSSer: an automated method to identify transcription start sites in prokaryotic genomes from differential RNA sequencing data},
  author={Hadi Jorjani and Mihaela Zavolan},
  journal={Bioinformatics},
  year={2014},
  volume={30 7},
  pages={971-4}
}
MOTIVATION Accurate identification of transcription start sites (TSSs) is an essential step in the analysis of transcription regulatory networks. In higher eukaryotes, the capped analysis of gene expression technology enabled comprehensive annotation of TSSs in genomes such as those of mice and humans. In bacteria, an equivalent approach, termed differential RNA sequencing (dRNA-seq), has recently been proposed, but the application of this approach to a large number of genomes is hindered by… CONTINUE READING
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