TSSC1 is novel component of the endosomal retrieval machinery

  title={TSSC1 is novel component of the endosomal retrieval machinery},
  author={David C. Gershlick and Christina E. M. Schindler and Yu Chen and Juan S. Bonifacino},
  journal={Molecular Biology of the Cell},
  pages={2867 - 2878}
A previously uncharacterized WD40 domain–containing protein named TSSC1 is shown to interact with the GARP and EARP tethering complexes, promoting retrograde transport of Shiga toxin from endosomes to the TGN, as well as recycling internalized transferrin from endosomes to the plasma membrane. 

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