TSH-receptor autoantibodies: pathophysiology, assay methods, and clinical applications.

@article{Ehlers2018TSHreceptorAP,
  title={TSH-receptor autoantibodies: pathophysiology, assay methods, and clinical applications.},
  author={Margret Ehlers and Stephanie Allelein and Matthias Schott},
  journal={Minerva endocrinologica},
  year={2018},
  volume={43 3},
  pages={
          323-332
        }
}
TSH receptor antibodies (TRAbs) are characteristic indicators for the common autoimmune thyroid disease Graves disease (GD). In almost all patients stimulating TRAbs are found leading to hyperthyroidism as these antibodies act in an agonistic manner to TSH. Besides stimulating TRAbs, other TRAbs are also frequently found leading to inhibition of TSH… CONTINUE READING