• Corpus ID: 55914114

TSH is Not the Answer: Rationale for a New Paradigm to Evaluate and Treat Hypothyroidism, Particularly Associated with Weight Loss

@inproceedings{Rowsemitt2011TSHIN,
  title={TSH is Not the Answer: Rationale for a New Paradigm to Evaluate and Treat Hypothyroidism, Particularly Associated with Weight Loss},
  author={Carol N. Rowsemitt and Thomas Najarian},
  year={2011}
}
While many endocrinologists continue to debate the appropriate levels of TSH to use as boundaries for normal limits, we believe using TSH to assess thyroid function is counterproductive, particularly in those patients attempting to lose weight. From the published literature and our own clinical experience, we have come to understand that the set point for metabolism is adjusted downward in the hypocaloric state. The decrease in metabolism is often referred to as part of the "famine response… 

Hypothyroidism, Particularly Associated with Weight Loss: Evaluation and Treatment based on Symptoms and Thyroid Hormone Levels

Two specific patient examples of this syndrome are given and the need to understand that there are limitations to the ability to detect every appropriate variable in any one patient is addressed, so that the value of any particular lab reading in anyone patient is not overestimated.

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