TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin.

Abstract

Nitric oxide (NO) is an unstable signalling molecule synthesized de novo mainly from L-arginine by NO synthase (NOS) enzymes. Nitrite reduction can also produce NO, predominantly within body fluids (for example, saliva, sweat and blood plasma) and under extreme hypoxic and acidic conditions. It remains unknown if intracellular canonical signalling pathways… (More)
DOI: 10.1038/ncomms1371

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