TRPV1 and Endocannabinoids: Emerging Molecular Signals that Modulate Mammalian Vision

@inproceedings{Ryskamp2014TRPV1AE,
  title={TRPV1 and Endocannabinoids: Emerging Molecular Signals that Modulate Mammalian Vision},
  author={Daniel A Ryskamp and Sarah Redmon and Andrew O. Jo and David Kri{\vz}aj},
  booktitle={Cells},
  year={2014}
}
Transient Receptor Potential Vanilloid 1 (TRPV1) subunits form a polymodal cation channel responsive to capsaicin, heat, acidity and endogenous metabolites of polyunsaturated fatty acids. While originally reported to serve as a pain and heat detector in the peripheral nervous system, TRPV1 has been implicated in the modulation of blood flow and osmoregulation but also neurotransmission, postsynaptic neuronal excitability and synaptic plasticity within the central nervous system. In addition to… CONTINUE READING
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