TRPC3 cation channel plays an important role in proliferation and differentiation of skeletal muscle myoblasts

@article{Woo2010TRPC3CC,
  title={TRPC3 cation channel plays an important role in proliferation and differentiation of skeletal muscle myoblasts},
  author={Jin Seok Woo and Chung-Hyun Cho and Do Han Kim and Eun Hui Lee},
  journal={Experimental & Molecular Medicine},
  year={2010},
  volume={42},
  pages={614-627}
}
During membrane depolarization associated with skeletal excitation-contraction (EC) coupling, dihydropyridine receptor [DHPR, a L-type Ca2+ channel in the transverse (t)-tubule membrane] undergoes conformational changes that are transmitted to ryanodine receptor 1 [RyR1, an internal Ca2+-release channel in the sarcoplasmic reticulum (SR) membrane] causing Ca2+ release from the SR. Canonical-type transient receptor potential cation channel 3 (TRPC3), an extracellular Ca2+-entry channel in the t… CONTINUE READING
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