TRPC Channels As Effectors of Cardiac Hypertrophy

@article{Eder2011TRPCCA,
  title={TRPC Channels As Effectors of Cardiac Hypertrophy},
  author={Petra Eder and J. Molkentin},
  journal={Circulation Research},
  year={2011},
  volume={108},
  pages={265–272}
}
Transient receptor potential (TRP) channels of multiple subclasses are expressed in the heart, although their functions are only now beginning to emerge, especially for the TRPC subclass that appears to regulate the cardiac hypertrophic response. Although TRP channels permeate many different cations, they are most often ascribed a specific biological function because of Ca2+ influx, either for microdomain signaling or to reload internal Ca2+ stores in the endoplasmic reticulum through a store… Expand
205 Citations
Role of TRP channels in the cardiovascular system.
  • 104
  • PDF
TRP Channels: Current Perspectives in the Adverse Cardiac Remodeling
  • 23
Characteristics of transient receptor potential canonical calcium-permeable channels and their relevance to vascular physiology and disease.
  • D. Beech
  • Medicine
  • Circulation journal : official journal of the Japanese Circulation Society
  • 2013
  • 66
TRP Channels Mediated Pathological Ca2+-Handling and Spontaneous Ectopy
  • 1
Cardiac Remodeling and Disease: SOCE and TRPC Signaling in Cardiac Pathology.
  • Petra Eder
  • Medicine, Biology
  • Advances in experimental medicine and biology
  • 2017
  • 29
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 85 REFERENCES
TRPC channels are necessary mediators of pathologic cardiac hypertrophy
  • 229
  • PDF
TRPC1 Channels Are Critical for Hypertrophic Signaling in the Heart
  • 181
Upregulation of TRPC1 in the development of cardiac hypertrophy.
  • 188
Increased Vascular Smooth Muscle Contractility in TRPC6−/− Mice
  • 447
  • PDF
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling.
  • 439
  • PDF
TRPC3 channels colocalize with Na+/Ca2+ exchanger and Na+ pump in axial component of transverse-axial tubular system of rat ventricle.
  • 53
Regulation of canonical transient receptor potential isoform 3 (TRPC3) channel by protein kinase G.
  • H. Kwan, Y. Huang, X. Yao
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 2004
  • 158
  • PDF
...
1
2
3
4
5
...